Programs - Training of the Pediatric Emergency Physician-Scientist

Principal Investigator/Program Director: David Schnadower, M.D., M.P.H.
Co-Program Director: F. Sessions Cole, M.D.
Research Fellow Support: 2 Postdocs (M.D.'s)

The long-term objective of this program is to use this funding to promote the career development of young physician-scientists who will become future leaders in biomedical research efforts dedicated to improving health outcomes for children with emergency medical conditions. The specific aims of this proposal are to identify potential trainees at the completion of their residency and to provide them with a solid research experience during their fellowship in the laboratory of a qualified mentor, or with a comparably rigorous mentored patient-oriented research experience. The focus of the research will be on child health issues in pediatric emergency medicine, including high-priority patient-oriented research with emphasis on the relationship between catastrophic illness, emergency care, and long-term disabilities and molecular mechanisms of infection and immunity, cardiopulmonary disease, and multiple organ dysfunction syndrome (MODS) among others.

We will achieve this goal by creating two tracks:

  1. patient-oriented research, and
  2. the molecular mechanisms of infection and immunity, cardiopulmonary disease, and MODS.

Recent advances in cell, molecular, and developmental biology will be applied to understanding the pathogenesis and treatment of infection and immunity, cardiopulmonary disease, and MODS. Similarly, rigorous patient-oriented research methods will be applied to improve outcomes of high-priority emergency medical and surgical diseases, using the full facilities of Washington University School of Medicine and its Department of Pediatrics. We have, in place, a structure in which bright, motivated, young pediatricians will flourish in a protected environment and will emerge as leaders in this evolving area of pediatrics. The long-term goals will be realized as its trainees contribute to the development of, and leadership as, pediatric physician-scientists during the next two or more decades.

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